Esophageal cancer is one of the leading causes of cancer-related deaths worldwide, and the need for advanced preclinical models to study its biology and treatment options is critical. Esophageal cancer PDX models (patient-derived xenograft models) have become an invaluable tool in cancer research, offering a more accurate representation of human tumors compared to traditional cell line-based models. These models are created by implanting patient tumor samples into immunodeficient mice, allowing researchers to evaluate the efficacy of new drugs, study tumor progression, and investigate personalized treatment strategies. The use of esophageal cancer PDX models significantly enhances our understanding of the disease and aids in the development of targeted therapies that can improve patient outcomes. With their ability to mimic the complexity of human tumors, esophageal cancer PDX models are expected to play a key role in the future of cancer research and drug discovery.
For more: https://www.creative-biolabs.com/3d-biology/pdx-derived-esophageal-cancer-organo [Post edited 18 Feb 5:48]
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